Autism and Brain Development

作者:Walsh Christopher A*; Morrow Eric M; Rubenstein John L R
来源:Cell, 2008, 135(3): 396-400.
DOI:10.1016/j.cell.2008.10.015

摘要

Genetic studies are refining our understanding of neurodevelopmental mechanisms in autism. Some autism-related mutations appear to disrupt genes regulated by neuronal activity, which are especially important in development of the postnatal nervous system. Gene replacement studies in mice indicate that the developmental window to ameliorate symptoms may be wider than previously anticipated.

  • 出版日期2008-10-31