A Hybrid IMRT/VMAT Technique for the Treatment of Nasopharyngeal Cancer

作者：Zhao, Nan; Yang, Ruijie^*; Jiang, Yuliang; Tian, Suqing; Guo, Fuxin; Wang, Junjie

来源：Biomed Research International, 2015, 2015: 940102.

DOI：10.1155/2015/940102

• VOLUMETRIC-MODULATED ARC
• SIMULTANEOUS INTEGRATED BOOST
• BEAM ANGLE OPTIMIZATION
• NECK-CANCER
• RADIATION-THERAPY
• RADIOTHERAPY
• HEAD
• IMRT
• VMAT
• CARCINOMA

Hybrid IMRT/VMAT technique which combined intensity modulated radiotherapy (IMRT) and volumetricmodulated arc therapy (VMAT) was developed for the treatment of nasopharyngeal cancer (NPC). Two-full-arc VMAT (2ARC-VMAT), 9-field IMRT (9F-IMRT), and Hybrid IMRT/VMAT plans for NPC were compared in terms of the dosimetric quality, sparing of organs at risk (OARs), and delivery efficiency. The Hybrid IMRT/VMAT technique can improve the target dose homogeneity and conformity compared with 9F-IMRT and 2ARC-VMAT. It can reduce the dose delivered to the TMJ, mandible, temporal lobe, and unspecified tissue with fewer MUs compared with 9F-IMRT and dose delivered to parotids, brainstem, and spinal cord compared with 2ARC-VMAT technique. The mean delivery time of Hybrid plans was shorter than that of 9F-IMRT plans (408 s versus 812 s; P = 0.00) and longer than that of 2ARC-VMAT plans (408 s versus 179 s; P = 0.00). Hybrid IMRT/VMAT technique could be a viable radiotherapy technique with better plan quality.

• 出版日期2015
• 单位北京大学