Antibacterial, Antiviral, Antioxidant and Antiproliferative Activities of Thymus guyonii Essential Oil

作者：Zeghib Assia; Kabouche Ahmed; Laggoune Souheila; Calliste Claude Alain; Simon Alain; Bressolier Philippe; Aouni Mahjoub; Duroux Jean Luc; Kabouche Zahia^*

来源：Natural Product Communications, 2017, 12(10): 1651-1654.

DOI：10.1177/1934578x1701201032

• Thymus
• Essential oil
• Antibacterial
• Antiviral
• Antioxidant
• Antiproliferative

The aerial parts of Thymus guyonii were hydrodistilled in a Clevenger type apparatus and analyzed by GC and GC-MS. 26 components were identified representing 99.8%, with carvacrol (55.6%), thymol (21.2%), o-cymene (9.7%) and delta-terpinene (5.7%) as the major components. T. guyonii essential oil exhibited a good bactericidal effect (MBC/MIC ratio = 2) against all the tested pathogenic bacteria. The essential oil lacks antiviral activity towards coxsackievinis B3 however it showed a good DPPH radical scavenging at 0.5 and 5 mg/mL test-concentrations (15.5 +/- 1.2% and 44.3 +/- 1.95%, respectively). The essential oil exhibited a proliferation inhibition of Human colorectal cell line HT-29 (30.4 +/- 3.4%) at 50 mu g/mL test-concentration.

• 出版日期2017-10