科研之友
微信
新浪微博
Facebook
分享链接
摘要
The DNA damage response (DDR), which is frequently activated in cancer cells, has been proposed to operate as an early barrier against oncogenesis. We have recently shown that ATM mediates the spontaneous regression of E mu-myc-driven murine B-cell leukemia in a natural killer and T cell-dependent manner. The DDR partially enhanced immune recognition by stimulating the expression of the DNAM-1 ligand CD155.
- 出版日期2013-6-1
