Differential blood-based biomarkers of psychopathological dimensions of schizophrenia

作者：Garcia Alvarez Leticia; Paz Garcia Portilla Maria; Gonzalez Blanco Leticia; Saiz Martinez Pilar Alejandra; de la Fuente Tomas Lorena; Menendez Miranda Isabel; Iglesias Celso; Bobes Julio

来源：Revista de Psiquiatria y Salud Mental, 2016, 9(4): 219-227.

DOI：10.1016/j.rpsm.2016.04.003

• Biomarkers
• Schizophrenia
• Cognition
• Positive symptoms
• Negative symptoms

Symptomatology of schizophrenia is heterogeneous, there is not any pathognomonic symptom. Moreover, the diagnosis is difficult, since it is based on subjective information, instead of markers. The purpose of this study is to provide a review of the current status of blood-based biomarkers of psychopathological dimensions of schizophrenia. Inflammatory, hormonal or metabolic dysfunctions have been identified in patients with schizophrenia and it has attempted to establish biomarkers responsible for these dysfunctions. The identification of these biomarkers could contribute to the diagnosis and treatment of schizophrenia.

• 出版日期2016-12