MARTINI Coarse-Grained Model for Crystalline Cellulose Microfibers

作者：Lopez Cesar A; Bellesia Giovanni; Redondo Antonio; Langan Paul; Chundawat Shishir P S; Dale Bruce E; Marrink Siewert J; Gnanakaran S^*

来源：Journal of Physical Chemistry B, 2015, 119(2): 465-473.

DOI：10.1021/jp5105938

Commercial-scale biofuel production requires a deep understanding of the structure and dynamics of its principal target: cellulose. However, an accurate description and modeling of this carbohydrate structure at the mesoscale remains elusive, particularly because of its overwhelming length scale and configurational complexity. We have derived a set of MARTINI coarse-grained force field parameters for the simulation of crystalline cellulose fibers. The model is adapted to reproduce different physicochemical and mechanical properties of native cellulose I beta. The model is able not only to handle a transition from cellulose I beta to another cellulose allomorph, cellulose IIII, but also to capture the physical response to temperature and mechanical bending of longer cellulose nanofibers. By developing the MARTINI model of a solid cellulose crystalline fiber from the building blocks of a soluble cellobiose coarse-grained model, we have provided a systematic way to build MARTINI models for other crystalline biopolymers.

• 出版日期2015-1-15