Aortic stenosis in a patient with Hurler's syndrome after bone marrow transplantation

作者：Watanabe Naruhito; Anagnostopoulos Petros V; Azakie Anthony^*

来源：Cardiology in the Young, 2011, 21(3): 349-350.

DOI：10.1017/S1047951110002015

• Mucopolysaccharidosis
• aortic valve replacement
• valvular disease

We describe a case of severe aortic stenosis in a 16-year-old male with Hurler's syndrome who had prior bone marrow transplantation. The excised aortic valve leaflets showed characteristic pathologic findings of Hurler's syndrome. This is the first case report of aortic valve replacement in a patient with Hurler's syndrome treated with bone marrow transplantation that demonstrates progression of the aortic valve disease despite treatment.

• 出版日期2011-6