A novel method for the high-pressure-promoted, uncatalyzed aza-Michael reaction of nitrogen heterocycles with enones in water

作者：Uddin Md Imam; Nakano Keiji; Ichikawa Yoshiyasu; Kotsuki Hiyoshizo^*

来源：Synlett, 2008, 2008(9): 1402-1406.

DOI：10.1055/s-2008-1072594

• aza-Michael reaction
• nitrogen heterocycles
• enones
• water
• high-pressure reaction

A new green chemical method for the aza-Michael reaction of nitrogen heterocycles with enones in water as a solvent without the use of any catalysts under high-pressure conditions is described.

• 出版日期2008-5-23