Aggregation of polylactide with carboxyl groups at one chain end in the presence of metal cations

作者：Bednarek Melania^*; Basko Malgorzata; Biedron Tadeusz; Kubisa Przemysaw; Pluta Mirosaw

来源：Polymer Bulletin, 2014, 71(8): 1891-1907.

DOI：10.1007/s00289-014-1162-x

• Activated monomer mechanism
• Biocompatible polymer
• Carboxyl groups
• Click chemistry
• Functionalizations
• Poly lactide
• Solution viscosity
• Stereocomplexes

Polylactides with one or more carboxyl groups at one chain end were synthesized by cationic polymerization according to activated monomer mechanism and by application of "thiol-yne" click chemistry for subsequent functionalization. End groups of such obtained polylactides were converted into ionic groups by neutralization of polymer solutions with metal oxides, mainly calcium oxide, and the aggregation of individual stereoisomers as well as that of the mixture of poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA) was investigated. The extent and progress of the aggregation was followed by viscosity measurements, and aggregated polymers in the solid state were examined by SEM and DSC. Solution viscosity increase was observed upon the aggregation of individual PLA stereoisomers, whereas PLA stereocomplex precipitation occurred in the case of the aggregation of PLLA/PDLA/metal oxide mixture.

• 出版日期2014
• 单位Polish Academy of Sciences