Automated motion correction using parallel-strip registration for wide-field en face OCT angiogram

作者:Zang, Pengxiao; Liu, Gangjun; Zhang, Miao; Dongye, Changlei; Wang, Jie; Pechauer, Alex D.; Hwang, Thomas S.; Wilson, David J.; Huang, David; Li, Dengwang*; Jia, Yali
来源:Biomedical Optics Express, 2016, 7(7): 2823-2836.
DOI:10.1364/BOE.7.002823

摘要

We propose an innovative registration method to correct motion artifacts for wide-field optical coherence tomography angiography (OCTA) acquired by ultrahigh-speed swept-source OCT (>200 kHz A-scan rate). Considering that the number of A-scans along the fast axis is much higher than the number of positions along slow axis in the wide-field OCTA scan, a non-orthogonal scheme is introduced. Two en face angiograms in the vertical priority (2 y-fast) are divided into microsaccade-free parallel strips. A gross registration based on large vessels and a fine registration based on small vessels are sequentially applied to register parallel strips into a composite image. This technique is extended to automatically montage individual registered, motion-free angiograms into an ultrawide-field view.