A Photochemical Route to 2-Substituted Benzo[b]furans

作者:Protti Stefano*; Fagnoni Maurizio; Albini Angelo
来源:Journal of Organic Chemistry, 2012, 77(15): 6473-6479.
DOI:10.1021/jo3010183

摘要

2-Substituted benzo[b]furans were synthesized by a one-step metal-free photochemical reaction between 2-chlorophenol derivatives and terminal alkynes by tandem formation of an aryl-C and a C-O bond via an aryl cation intermediate. The mild conditions and the application to chlorophenols rather of the more expensive bromo or iodo analogues makes this procedure environmentally convenient.

  • 出版日期2012-8-3