Nanoparticles selectively immobilized onto large arrays of gold micro and nanostructures through surface chemical functionalizations

作者：Palazon Francisco; Rojo Romeo Pedro; Chevalier Celine; Gehin Thomas; Belarouci Ali; Cornillon Amandine; Zuttion Francesca; Phaner Goutorbe Magali; Souteyrand Eliane; Chevolot Yann; Cloarec Jean Pierre^*

来源：Journal of Colloid and Interface Science, 2015, 447: 152-158.

DOI：10.1016/j.jcis.2014.11.028

• Self-assembly
• Nanoantenna
• Colloid
• Surface functionalization

Latex nanoparticles (100 nm and 200 nm diameter) were precisely located onto the gold regions of micro and nanopatterned gold/silica substrates through surface chemical functionalizations. The gold patterns were selectively functionalized with alkylthiols bearing biotin or amine headgroups. This selective functionalization allowed the trapping of streptavidin- or carboxy-functionalized latex nanoparticles onto the gold structures with very little non-specific adsorption onto the surrounding silica. Quantitative data of nanoparticle capture on gold and silica, obtained through SEM image analysis, showed a one to two order of magnitude increase on gold with a similar low coverage on silica (non-specific adsorption) thanks to chemical functionalizations. Single nanoparticles were captured at the gap of dimer gold nanostructures.

• 出版日期2015-6-1