Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Chloranthus japonicus Sieb.

作者:Kang Tae Hoon; Lee Yun Me; Lee Won Jung; Hwang Eui Il; Park Ki Duk; Choi Gyung Ja; Moon Jae Sun; Park Ho Yong; Kim Sung Uk*
来源:Journal of Microbiology and Biotechnology, 2017, 27(7): 1272-1275.
DOI:10.4014/jmb.1612.12051

摘要

Two dimeric sesquiterpenes were separated from Chloranthus japonicus Sieb. and identified as shizukaols C and F. They exhibited potent antifungal activities (MICs = 4-16 mu g/ml) in vitro against various plant pathogenic fungi (Pythium ultimum, Phytophthora infestans, Botrytis cinerea, Colletotrichum lagenarium, Alternaria kikuchiana, and Magnaporthe grisea). Shizukaol C showed 88% and 91% protective activities in the greenhouse against Puccinia recondita (wheat leaf rust) and Phytophthora infestans (tomato late blight), respectively, at 100 mu g/ml; shizukaol F exhibited 93% antifungal activity against Puccinia recondita at the same concentration. Therefore, these compounds might serve as interesting candidates for effective antifungal agents.

  • 出版日期2017-7