Application of RNA interference in plants

作者：Angaji S Abdolhamid^*; Hedayati Sara Sadate; Poor Reihane Hosein; Poor Sanaz Samad; Shiravi Shima; Madani Safoura

来源：Plant Omics, 2010, 3(3): 77-84.

• Gene silencing
• miRNA
• siRNA

Gene silencing can occur either through repression of transcription, termed transcriptional gene silencing (TGS), or through mRNA degradation, termed post-transcriptional gene silencing (PTGS). TGS results in reduction of transcription whereas PTGS results in sequence specific mRNA degradation in cytoplasm without dramatic changes in transcription of corresponding gene in nucleus. Both TGS and PTGS are used to regulate endogenous genes. Interestingly, mechanisms of gene silencing also protect the organism's genome from transposons, viruses. In this paper, molecular aspects and mechanisms of gene silencing in plant were reviewed. Finally, its applications were discussed.

• 出版日期2010-5