Awareness and Preferences Regarding BRCA1/2 Genetic Counseling and Testing Among Latinas and Non-Latina White Women at Increased Risk for Hereditary Breast and Ovarian Cancer

作者：Gammon Amanda Dawn^*; Rothwell Erin; Simmons Rebecca; Lowery Jan T; Ballinger Lori; Hill Deirdre A; Boucher Kenneth M; Kinney Anita Yeomans

来源：Journal of Genetic Counseling, 2011, 20(6): 625-638.

DOI：10.1007/s10897-011-9376-7

• BRCA1 and BRCA2
• Genetic counseling
• Genetic testing
• Latinos
• Hereditary breast and ovarian cancer
• Awareness
• Preferences

This study was an investigation of awareness, cognitions, and psychosocial and educational needs related to genetic counseling and testing among Latinas and non-Latina whites at increased risk for having a BRCA1/2 mutation. Sixty-three Latina and eighty-four non-Latina white women completed telephone surveys employing a mixture of quantitative and qualitative questions assessing awareness, benefits, risks, barriers, and genetic counseling communication preferences regarding BRCA1/2 testing. Among participants who had not previously had genetic counseling/testing, 56.9% of Latinas (29/51) and 34.8% of non-Latina white participants (24/69) were unaware of the availability of BRCA1/2 testing. In multivariate logistic regression analysis, Latina ethnicity was the only statistically significant independent factor associated with lack of awareness (OR = 0.42; 95% CI = 0.19-0.35). No appreciable differences were noted between ethnic groups regarding perceived benefits of BRCA1/2 testing or desired genetic counseling topics. These findings underscore the importance of increasing awareness of cancer genetic counseling and genetic testing among both Latina and non-Latina white populations.

• 出版日期2011-12