Short-term and Long-term Efficacy of Psychological Therapies for Irritable Bowel Syndrome: A Systematic Review and Meta-analysis

作者：Laird Kelsey T; Tanner Smith Emily E; Russell Alexandra C; Hollon Steve D; Walker Lynn S

来源：Clinical Gastroenterology and Hepatology, 2016, 14(7): 937-+.

DOI：10.1016/j.cgh.2015.11.020

• Abdominal Pain
• Empirically Supported Therapies
• Evidence-based Treatment
• Functional Gastrointestinal Disorder

BACKGROUND & AIMS: Several meta-analyses have demonstrated the efficacy of psychological therapies for reducing gastrointestinal (GI) symptoms in patients with irritable bowel syndrome (IBS). However, no meta-analysis has investigated the duration of these effects. We performed a meta-analysis to assess the immediate, short-term, and long-term efficacy of psychotherapy for reducing GI symptoms in adults with IBS.
METHODS: We searched PubMed, PsycINFO, Science Direct, and ProQuest Dissertations and Theses through August 15, 2015 for randomized controlled trials that compared psychological therapy with an active or non-active comparison (control) condition for treatment of GI symptoms in adults with IBS.
RESULTS: Forty-one trials were included in our meta-analysis, comprising data from 2290 individuals (1183 assigned to psychotherapy and 1107 assigned to a control condition). Compared with a mixed group of control conditions, psychological therapies had a medium effect on GI symptom severity ((d) over bar = 0.69) immediately after treatment. On average, individuals who received psychotherapy had a greater reduction in GI symptoms after treatment than 75% of individuals assigned to a control condition. After short-term follow-up periods (1-6 months after treatment) and long-term follow-up periods (6-12 months after treatment), this effect remained significant and medium in magnitude ((d) over bar = 0.76 and (d) over bar = 0.73, respectively).
CONCLUSIONS: Psychological therapies reduce GI symptoms in adults with IBS. These effects remained significant and medium in magnitude after short-term and long-term follow-up periods.

• 出版日期2016-7