ADVANTAGES OF USING THIN ENDOSCOPE-ASSISTED ENDOSCOPIC SUBMUCOSAL DISSECTION TECHNIQUE FOR LARGE COLORECTAL TUMORS

作者：Uraoka Toshio^*; Ishikawa Shin; Kato Jun; Higashi Reiji; Suzuki Hideyuki; Kaji Eisuke; Kuriyama Motoaki; Saito Shunsuke; Akita Mitsuhiro; Hori Keisuke; Harada Keita; Ishiyama Shuhei; Shiode Junji; Kawahara Yoshiro; Yamamoto Kazuhide

来源：Digestive Endoscopy, 2010, 22(3): 186-191.

DOI：10.1111/j.1443-1661.2010.00992.x

• colonic neoplasms
• colonoscopy
• endoscopic submucosal dissection
• endoscopy
• gastrointestinal
• traction system

Background:
Our purpose was to evaluate the effectiveness of a newly developed non-invasive traction technique known as thin endoscope-assisted endoscopic submucosal dissection (TEA-ESD) procedure for the removal of colorectal laterally spreading tumors (LST).
Patients and Methods:
A total of 37 LST located in the rectum and distal sigmoid colons of 37 patients were eligible for outcome analysis. Twenty-one LST were treated with TEA-ESD and were then retrospectively compared to 16 LST that had previously been treated with standard ESD. Tumor size, en bloc resection rate, procedure time, combined number of different electrical surgical knives used during each procedure and associated complications were evaluated in this case-control study.
Results:
There was no statistically significant difference in tumor size between the TEA-ESD group and the ESD control group (43.6 +/- 16 mm and 42.4 +/- 14 mm, respectively). All LST were successfully resected en bloc in both groups. Procedure duration was shorter for the TEA-ESD group than the ESD control group, although the difference was not statistically significant (96 +/- 53 minutes vs 116 +/- 74 minutes; P = 0.18). The percentage of cases in which only one electrical surgical knife was used during the entire procedure was significantly higher in the TEA-ESD group compared to the ESD control group (85.7% vs 31.3%; P = 0.0005). There were no perforations in the TEA-ESD group while the ESD control group experienced one perforation. At the present time, TEA-ESD is limited to the rectum and distal sigmoid colon.
Conclusion:
It was technically easier, safer and more cost-effective to perform ESD for LST in the rectum and the distal sigmoid colon using the newly developed TEA-ESD traction technique.

• 出版日期2010-7