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摘要
The synthesis and characterization of two novel pyran derivatives (1 and 2) were realized by means of IR, 1H NMR, HRMS and single crystal X-ray crystallography. The anticancer activity of the two compounds were investigated against four human cancer cell lines (GES-1, SGC-7901, BGC-823 and MGC-803) by MTT assay. In addition, the relationship between activity and structure of the two compounds was further investigated through molecular docking study.
- 出版日期2018
- 单位浙江省肿瘤医院
