Adipose-Derived Stem Cells: Isolation, Characterization, and Differentiation Potential

作者:Huang Shyh Jer; Fu Ru Huei; Shyu Woei Cherng; Liu Shih Ping; Jong Gwo Ping; Chiu Yung Wei; Wu Hsiao Su; Tsou Yung An; Cheng Chao Wen; Lin Shinn Zong*
来源:Cell Transplantation, 2013, 22(4): 701-709.
DOI:10.3727/096368912X655127

摘要

In mammals, the two main types of adipose tissues, white and brown adipose tissues, exert different physiological functions. White adipose tissue (WAT) is for storing energy, while brown adipose tissue (BAT) is for energy consumption. Adipose-derived stem cells (ADSCs) are abundant in WAT and BAT, have multipotent characteristics, and are easily extracted. ADSCs can be differentiated into several cell lineages, including adipocytes, osteoblasts, chondrocytes (cartilage cells), myocytes, and neuronal cells. Therefore, ADSC could be considered as a strategy for future regenerative medicine and tissue engineering.