The Effects of Ginger on Gallbladder Motility in Healthy Male Humans

作者：Chuah Seng Kee; Wu Keng Liang^*; Tai Wei Chen; Changchien Chi Sin

来源：Journal of Neurogastroenterology and Motility, 2011, 17(4): 411-415.

DOI：10.5056/jnm.2011.17.4.411

• Abdomen
• Gallbladder
• Ginger
• Ultrasonography

Background/Aims
Ginger has been used to treat a number of diseases including those affecting the digestive tract. This study was aimed to investigate the effects of ginger on gallbladder volume and gastrointestinal sensation in healthy male subjects.
Methods
Nineteen healthy male volunteers (age 21.3 +/- 3.9 years, body mass index 21.6 +/- 1.9 kg/m2) were studied on 2 occasions in a double blind randomized crossover design. After ingesting ginger (1,200 mg) or placebo capsules (starch), abdominal ultrasound was used to measure the gallbladder volume (calculated from gallbladder width, depth and diameter) and ejection fraction following a standard test meal. Gastrointestinal symptoms were also recorded at regular intervals by visual analogue scales.
Results
There were no differences in gallbladder volume or ejection fraction between ginger and placebo. Abdominal symptoms of bloating, fullness, nausea, discomfort and hunger was not different between the 2 occasions. Conclusions
Ginger (1,200 mg) may not affect gallbladder ejection fraction and possible relevant abdominal symptoms in healthy male human subjects.

• 出版日期2011-10
• 单位长春大学