Application of Traditional Chinese Medical Herbs in Prevention and Treatment of Respiratory Syncytial Virus

作者:Lin Li Li; Shan Jin Jun*; Xie Tong; Xu Jian Ya; Shen Cun Si; Di Liu Qing; Chen Jia Bin; Wang Shou Chuan*
来源:Evidence-Based Complementary and Alternative Medicine, 2016, 2016: 6082729.
DOI:10.1155/2016/6082729

摘要

Respiratory syncytial virus (RSV) is a common viral pathogen of the lower respiratory tract, which, in the absence of effective management, causes millions of cases of severe illness per year. Many of these infections develop into fatal pneumonia. In a review of English and Chinese medical literature, recent traditional Chinese medical herb- (TCMH-) based progress in the area of prevention and treatment was identified, and the potential anti-RSV compounds, herbs, and formulas were explored. Traditional Chinese medical herbs have a positive effect on inhibiting viral attachment, inhibiting viral internalization, syncytial formation, alleviation of airway inflammation, and stimulation of interferon secretion and immune system; however, the anti-RSV mechanisms of TCMHs are complicated, which should be further investigated.