Health-care utilization and respiratory morbidities in preterm infants with pulmonary hypertension

作者：Stuart B D; Sekar P; Coulson J D; Choi S E J; McGrath Morrow S A; Collaco J M^*

来源：Journal of Perinatology, 2013, 33(7): 543-547.

DOI：10.1038/jp.2012.170

• bronchopulmonary dysplasia
• chronic lung disease
• prematurity
• pulmonary hypertension

OBJECTIVE: To assess health-care utilization and risk of respiratory morbidities in preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH).
STUDY DESIGN: Retrospective data were obtained from subjects (n = 109) attending a BPD clinic. Subjects were stratified by the presence or absence of PH before and after 2 months of age. Analytic methods included t-tests, chi(2) tests and regression.
RESULT: Subjects with BPD and PH present after 2 months of age were hospitalized for 2.2 months longer than those without PH (P = 0.02). These subjects were 4.5 times more likely to receive home supplemental oxygen or mechanical ventilation (P = 0.03). No difference in the risk of respiratory morbidities after initial hospital discharge was seen with PH.
CONCLUSION: PH in preterm infants is associated with longer initial hospitalizations and a higher likelihood of requiring home respiratory support. This has implications for counseling families and reducing the medical, psychosocial, and economic burden of BPD and PH.

• 出版日期2013-7