Antifungal Activity of Morinol B Derivatives of Tetrahydropyran Sesquilignan

作者：Masuda Kenta; Nishiwaki Hisashi; Akiyama Koichi; Yamauchi Satoshi^*; Maruyama Masafumi; Sugahara Takuya; Kishida Taro

来源：Bioscience Biotechnology and Biochemistry, 2010, 74(10): 2071-2076.

DOI：10.1271/bbb.100422

• morinol B
• sesquilignan
• antifungal activity

The relationship between the structure of naturally occurring (7R,7'R,8R,8'R)-morinol B and its antifungal activity was examined. 3-Demethoxy morinol B showed much higher activity than the natural compound. The activity of the 4-butoxy-3-demethoxy derivative was higher than that of 3-demethoxy morinol B.

• 出版日期2010-10