Methyl imidazolate-bridged homo (Cu(II)-Cu(II)) and hetero (Cu(II)-Zn(II)) binuclear complexes. Plausible models for the chemistry of Cu-Zn superoxide dismutase

作者：Patel R N^*

来源：Oxidation Communications, 2006, 29(3): 602-612.

• homo (Cu(II)-Cu(II)) and hetero (Cu(II)-Zn(II)) binuclear complexes
• e.s.r.
• superoxide dismutase activity
• antibacterial activity
• methyl imidazolate-bridged

Synthesis, magnetic and X-band e.s.r. spectra were reported for a homo (Cu(II)Cu(II)) and hetero (Cu(II)-Zn(II)) binuclear methyl imidazolate bridged complexes using 2,2'-bipyridyl (Bipy) as capping ligand. Antibacterial and superoxide dismutase activity of these compounds was also measured. From pH,dependent e.s.r. and electronic spectral studies, complex [(Bipy)(2)Cu-2Me-Im-Cu(Bipy)(2)](ClO4)(3)center dot CH3OH (where 2Me-Im = 2-methyl imidazolate ion) was found to be stable in pH range 8.5 to 10.5 and complex [(Bipy)(2)Cu-2Me-Im-Zn(Bipy)(2)](BF4)(3) above 8.5 pH only. All the observations indicate that these complexes act as possible model for superoxide dismutase.

• 出版日期2006