科研之友
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摘要
The asymmetric cross-aldol reaction of formaldehyde with aldehyde pronucleophiles, catalyzed by trifluoromethyl-substituted diarylprolinol 1, was accomplished to directly afford alpha-hydroxymethyl-substituted aldehydes in good yield with excellent enantioselectivity.
- 出版日期2014-4-5
