Diversity Oriented Synthesis of Pyran Based Polyfunctional Stereogenic Macrocyles and Their Conformational Studies

作者：Ajay Arya; Sharma Shrikant; Gupt Munna Prasad; Bajpai Vikas; Hamidullah; Kumar Brijesh; Kaushik Mahabir Prasad; Konwar Rituraj; Ampapathi Ravi Sankar^*; Tripathi Rama Pati

来源：Organic Letters, 2012, 14(17): 4306-4309.

DOI：10.1021/ol3022275

A new approach to synthesize a homologous series of 14-, 15-, and 16-membered drug-like, macrocyclic glycoconjugates involving TBAHS promoted azide-propenone intramolecular cycloaddition in designed C-glycopyranosyl butenones from a simple sugar D-glucose and D-mannose is reported.

• 出版日期2012-9-7