Using Objective Response Detection techniques for detecting the tibial somatosensory evoked response with different stimulation rates

作者：Melges Danilo Barbosa^*; Catelli Infantosi Antonio Fernando; Leite Miranda de Sa Antonio Mauricio Ferreira

来源：Journal of Neuroscience Methods, 2011, 195(2): 255-260.

DOI：10.1016/j.jneumeth.2010.12.003

• Electroencephalogram
• Somatosensory evoked potential
• Stimulus frequency
• Objective Response Detection techniques
• Magnitude-Squared Coherence
• Component Synchrony Measure

This work investigates the influence of the stimulus frequency in the performance of two Objective Response Detection (ORD) techniques, the Magnitude-Squared Coherence (MSC) and the Component Synchrony Measure (CSM), as applied in somatosensory stimulation. Electroencephalographic signals were collected (10-20 International System) from forty adult volunteers without history of neurological pathologies. The stimuli were applied to the right posterior tibial nerve at the frequencies of 2, 5, 7 and 9 Hz and motor threshold intensity level. The detection was based on the rejection of the null hypothesis of response absence (significance level alpha = 0.05 and M = 100 and 500 epochs). The performances of the MSC at the four stimulation frequencies were compared, two-by-two, using the Proportion Test applied to the mean percentage rates in the total (2-100 Hz) and optimal (20-60 Hz) bands. The same was proceeded to the CSM. The evaluated derivations were Cz, C4, Pz and P4. No significant difference was found for any studied technique (MSC or CSM), any M-value, at any derivation. Thus, the highest stimulation frequency (9 Hz) can be used in order to obtain a reduction in the time of response detection in an ORD approach for a fixed M-value.

• 出版日期2011-2-15