科研之友
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摘要
ObjectivesTo determine the effect of asthma on functional limitations of older adults in the United States. DesignAnalyses were conducted with data from the Asthma Beliefs and Literacy in the Elderly study, a prospective cohort study of people aged 60 and older with asthma. SettingParticipants were recruited from urban primary care and pulmonary specialty practices in New York City and Chicago between 2010 and 2012. ParticipantsIndividuals aged 60 and older with asthma (380 women, 72 men, mean age 67.56.8 (range 60-98), 40% Latino, 30% black). MeasurementsCharacteristics of participants with and without activity of daily living (ADL) limitations were compared using the chi-square test. Generalized estimating equations were used to model the relationships between poor asthma control (Asthma Control Questionnaire (ACQ) score >1.5) and severity of airway obstruction (forced expiratory volume in 1-second (FEV1)) and number of ADL limitations. ResultsParticipants with one or more ADL limitations were more likely to be female (90% vs 81%, P=.02) and Latino (58% vs 32%, P<.001), have less than a high school education (53% vs 27%, P<.001) and an income of $1,350 per month or less (79% vs 46%, P<.001), and be unmarried (78% vs 64%, P=.003). In the adjusted analysis, poorer ACQ scores (odds ratio (OR)=1.6, 95% confidence interval (CI)=1.0-2.4; P=.05) but not severity of airway obstruction (OR=1.1, 95% CI=0.6-1.9) was associated with greater ADL limitations. ConclusionOlder adults reporting poor asthma control are more likely to have ADL limitations than those with controlled asthma, although one-time spirometry may not adequately identify those at risk of physical impairment from asthma.
- 出版日期2016-5
- 单位西北大学
