Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin

作者：Song, Yanling; An, Yuan; Liu, Weizhi; Hou, Wanfu; Li, Xingrui; Lin, Bingqian; Zhu, Zhi; Ge, Shengxiang^*; Yang, Huang-hao^*; Yang, Chaoyong^*

来源：Chemical communications, 2017, 53(86): 11774-11777.

DOI：10.1039/c7cc07231g

• OF-CARE DIAGNOSTICS
• CARDIAC MARKERS
• WHOLE-BLOOD
• CHEST-PAIN
• TROPONIN-I
• POINT
• DEVICE
• ELISA
• CHIP

This paper describes a centrifugal micropipette-tip method for ELISA sample processing combined with a pressure meter for portable quantitative detection of acute myocardial infarction (AMI) biomarker myoglobin (Myo). The method enables sensitive and reliable quantification of Myo in 35 minutes. With the advantages of simplicity, speed, user friendliness, low cost, and small sample consumption, centrifugal micropipette-tip ELISA shows great potential for quantitative POC diagnostics for AMI.

• 出版日期2017-11-7
• 单位厦门大学; 福州大学