Added Value of Parotid R2*Values for Evaluation of Sjogren Syndrome: A Preliminary Study

作者：Chu, Chen; Zhou, Nan; Zhang, Huayong; Dou, Xin; Li, Ming; Liu, Song; Wang, Jie; Chen, Weibo; Chan, Queenie; Sun, Lingyun^*; He, Jian^*; Zhou, Zhengyang^*

来源：Journal of Computer Assisted Tomography, 2017, 41(4): 547-552.

DOI：10.1097/RCT.0000000000000554

• R2*values
• Sjogren syndrome
• Parotid gland
• Magnetic resonance image

Objective: To explore the application of parotid R2* values for evaluating Sjogren syndrome (SS). @@@ Methods: Twenty-four consecutive SS patients and 24 sex-matched and age-matched healthy volunteers underwent bilateral parotid 3.0 T magnetic resonance (MR) imaging, including blood oxygenation level dependent sequence. Parotid R2* values of SS patients and volunteers were compared. A receiver operating characteristic analysis was used to evaluate the diagnostic performance of parotid R2* value alone and in combination with MR nodular grade. @@@ Results: The left parotid R2* value was significantly lower than the right (P = 0.006) in SS patients. Parotid R2* value in SS patients was significantly lower than that in healthy volunteers (P < 0.001). With a cutoff value of 64.14/s, the sensitivity of the parotid R2* value was 62.5% in the diagnosis of SS. By combining R2* value with MR nodular grade, the sensitivity reached 87.5%. @@@ Conclusions: Parotid R2* value contributed to the diagnosis of Sjgren syndrome combined with MR nodular grade.

• 单位
  南京大学