A Plea for the Newborn Diagnosis of Hb S-Hereditary Persistence of Fetal Hemoglobin

作者：Serjeant Graham R^*; Serjeant Beryl E; Hambleton Ian R; Oakley Matthew; Thein Swee Lay; Clark Barnaby

来源：Hemoglobin, 2017, 41(3): 216-217.

DOI：10.1080/03630269.2017.1360336

• Hereditary persistence of fetal hemoglobin (HPFH) genes
• Jamaica
• newborn screening
• school screening

The gene for hereditary persistence of fetal hemoglobin (HPFH) in the Caribbean is much more common than previously estimated. To avoid labeling persons with the benign syndrome Hb S (HBB: c.20A>T)/HPFH as a disease and wasting scarce resources, parental studies are recommended when newborn screening reveals a pattern consistent with an SS phenotype.

• 出版日期2017