科研之友
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摘要
This paper describes silver catalyzed synthesis of substituted phenanthrenes and naphthothiophenes from ortho-alkylated biaryl derivatives via 6-endo-dig intramolecular alkyne-arene coupling. The mechanistic study reveals that 6-endo-dig cyclization proceeds through initial p-coordination of the alkyne unit followed by a Friedel-Crafts-type electrophilic aromatic cyclization at the adjacent arene ring. X-ray crystallographic studies further supported the formation of carbocycles.
- 出版日期2017-9-7
