科研之友
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摘要
Diabetes is a cluster of clinical manifestations caused by impaired insulin secretion and/or its decreased biological effectiveness (insulin resistance) characterized by chronic metabolic disorders involving all the systems. In Shanghai, a senescence city in China, diabetes has become one of the diseases severely threatening the life of community populations. Shanghai Municipal Center for Disease Control and Prevention launched a large scale epidemiological survey on diabetes in order to find out the prevalence of diabetes and impaired glucose tolerance, as well as the characteristics of the associated risk factors in Shanghai community populations, to finally provide a basis for the community diabetes intervention. A stratified random sampling method was used in our cross sectional study both in rural and urban area residents aged from 15 to 74 years. A total of 14401 subjects were enrolled into the study, among them 11589 accomplished all the items of the survey, with a responding rate of 80.5%. In subjects accomplishing the survey, 4621 were males (39.9%), 6968 females (60.1%), 6500 (56.1%) from urban and 5089 (43.9%) from rural area. The prevalence of diabetes (DM), impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) was 8.6%(1000/11589), 6.9%(802/11589) and 1.0%(120/11589) separately, and was 5.00%, 4.86% and 0.74% after standardized by global population. In males, the prevalence of DM, IGT and IGF was 8.9%(412/4621), 6.4%(296/4621) and 1.0%(47/4621) separately, and was 5.32%, 4.93% and 0.82% after standardization; and in females, was 8.4%(588/6968), 7.3%(506/6968) and 1.0%(73/6968) separately, and was 4.66%, 4.78% and 0.66% after standardization. There existed no statistic significance between males and females in the prevalence of DM, IGT and IFG. The prevalence of DM, IGT and IFG was 11.2%(730/6500), 6.4%(419/6500) and 1.2%(77/6500) in the urban and 5.3%(270/5089), 7.5%(383/5089) and 0.8%(43/5089) in the rural. Statistic significance existed only in the prevalence of DM and IGT (P<0.05), but IFG. There was a tendency of increasing the prevalence of DM, IGT and IFG with the increasing of age, BMI and WC. Among the diabetics, the newly diagnosed cases were 39.6% and 69.3% in the urban and rural areas respectively, with the latter 1.49 times as high as the former (P<0.0001). Logistic regression analysis showed that the independent risk factors of DM and IGT were age, BMI, WC, hypertension and TG in the population; in males, living in the urban area, family history of diabetes, and cholesterol level were the risk factors of DM, and the only risk factor of IGT was total cholesterol level; while in females, living in the urban area, educational level, family history of diabetes and cholesterol level were the risk factors of DM, and educational level was the risk factor of IGT There did exist a tendency of increasing the prevalence of diabetes, and much attention, including DM screening, ought to be paid to the population in countryside, especially with rapid economic development.
- 出版日期2007
- 单位上海市疾病预防控制中心
