Usefulness of F-18 FDG PET/CT in the Follow-up of POEMS Syndrome After Autologous Peripheral Blood Stem Cell Transplantation

作者：Stefanelli Antonella; Treglia Giorgio^*; Leccisotti Lucia; Laurenti Luca; Luigetti Marco; Sabatelli Mario; Giordano Alessandro

来源：Clinical Nuclear Medicine, 2012, 37(2): 181-183.

DOI：10.1097/RLU.0b013e31823ea154

• F-18 FDG
• PET/CT
• stem cell transplantation
• POEMS syndrome

We report a case of a patient with relapse of POEMS syndrome (peripheral neuropathy, organomegaly, endocrinopathy, monoclonal plasma proliferative disorder, skin changes) that occurred 6 years after an autologous peripheral blood stem cell transplantation. F-18 FDG PET/CT showed several hypermetabolic as well as nonhypermetabolic bone lesions. Based on these findings, the patient was referred for radiotherapy to the hypermetabolic bone lesions. After autologous peripheral blood stem cell transplantation, F-18 FDG PET/CT may play a pivotal role in detecting new bone lesions in patients with POEMS syndrome, which may be treated by a focalized radiotherapy and/or systemic therapy.

• 出版日期2012-2