A new benzophenone from Dobinea delavayi

作者：Cheng, Zhong-Quan^*; Yang, Dan; Ma, Qing-Yun; Yi, Xin-Hui; Zhou, Jun; Zhao, You-Xing

来源：Chemistry of Natural Compounds, 2013, 49(1): 46-48.

DOI：10.1007/s10600-013-0502-7

• Dobinea delavayi
• benzophenone
• dobiniside A

A new benzophenone sesquiterpene dobiniside A (1), together with two known compounds, 4',6-dihydroxy-2,3',4-trimethoxybenzophenone (2) and mangiferin (3), were isolated from the root of Dobinea delavayi. The structure of the new compound was determined on the basis of spectroscopic analysis, including 1D, 2D NMR, and FAB-MS techniques as well as by comparison of the spectral data with those of related compounds reported in the literature. Compounds 1-3 were screened for antitumor activity in vitro, and compound 3 was shown to possess antitumor activity with IC50 value of 7.4 x 10(-5) mu M for A-549.

• 出版日期2013-3
• 单位中国科学院昆明植物研究所; 植物化学与西部植物资源持续利用国家重点实验室; 中国热带农业科学院; 桂林师范高等专科学校