A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation

作者：Chalortham Nopphadol^*; Leesawat Phuriwat; Ruangrajitpakorn Taneth; Supnithi Thepchai

来源：IEICE Transactions on Information and Systems, 2011, E94D(3): 448-455.

DOI：10.1587/transinf.E94.D.448

• ontology
• generic drug production
• tablet production supporting system
• drug formulation

This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.

• 出版日期2011-3