Desymmetrisation of aromatic diamines and synthesis of non-symmetrical thiourea derivatives by click-mechanochemistry

作者：Strukil Vjekoslav; Margetic Davor; Igrc Marina D; Eckert Maksic Mirjana^*; Friscic Tomislav

来源：Chemical communications, 2012, 48(78): 9705-9707.

DOI：10.1039/c2cc34013e

ortho- and para-Phenylenediamines were desymmetrised and quantitatively transformed into mono-and bis-(thio)ureas or mixed thiourea-ureas through a one-pot mechanochemical click reaction sequence; mechanochemical desymmetrisation proceeds quantitatively without excess reagents and allows the controlled extension of a molecular structure by combining normally competing reactions.

• 出版日期2012