Ni0.1Co0.9Fe2O4-based electrochemical sensor for the detection of paracetamol

作者：Vidyadharan Anitha Kumary^*; Jayan Divya; Nancy T E Mary

来源：Journal of Solid State Electrochemistry, 2014, 18(9): 2513-2519.

DOI：10.1007/s10008-014-2476-1

• Paracetamol
• Cyclic voltammetry
• Chronoamperometry
• Dopamine

A novel electrochemical sensor based on nickel-doped cobalt ferrite nanoparticles (Ni0.1Co0.9Fe2O4)-modified glassy carbon electrode (NCF/GCE) was presented for the sensitive detection of paracetamol. Experimental conditions such as pH, applied potentials and concentration were investigated using cyclic voltammetric and chronoamperometric techniques. The modified electrode exhibited excellent catalytic response towards the oxidation of paracetamol with good reproducibility. The overpotential for oxidation of paracetamol is decreased, and the current response enhanced significantly on the modified electrode in comparison with that of bare electrode. Linear calibration curve is obtained over the range 2 mu M to 8,000 mu M having a detection limit of 11 nM. The modified electrode facilitated the simultaneous detection of paracetamol, ascorbic acid, and dopamine with good reproducibility.

• 出版日期2014-9