An Efficient and Green Synthesis of Benzylidene-2-N-(carbothioamido)-6-oxo-1,2,5,6-tetrahydro-1-NH-1,2,4-tri azine Derivatives and their Antibacterial Activity Evaluation

作者：Rani V Anitha^*; Kumari Y Bharati

来源：Asian Journal of Chemistry, 2014, 26(18): 5931-5934.

DOI：10.14233/ajchem.2014.16333

• Green synthesis
• 1,2,4-Triazine derivatives
• Antibacterial activity

An efficient and green synthesis of (Z)-3-allkyl-5(benzylidene/substituted benzylidene)-2N-(carbothioamido)-6-oxo-1,2,5,6-tetrahydrol-NH-1,2,4-triazine derivatives have been developed in good yields and tested t for their antibacterial activities against Esc/zerichia coli, Proindencia aeruginosa, Pseudomonas azotogensis and Baccilus subtillis. Some of the synthesized compounds possess good activity against Bscherichia coli and Baccilus subtillis compared to standard drug streptomycin.

• 出版日期2014-9