Aspergiolide A, a novel anthraquinone derivative with naphtho[1,2,3-de]chromene-2,7-dione skeleton isolated from a marine-derived fungus Aspergillus glaucus

作者：Du Lin; Zhu Tianjiao; Fang Yuchun; Liu Hongbing; Gu Qianqun^*; Zhu Weiming

来源：Tetrahedron, 2007, 63(5): 1085-1088.

DOI：10.1016/j.tet.2006.11.074

• Aspergillus glaucus
• naphtho[1,2,3-de]chromene-2,7-dione
• aspergiolide
• microorganism
• fungus

Aspergiolide A (1), an anthraquinone derivative with naphtho [ 1,2,3 -de] chromene-2,7-di one skeleton, has been isolated from cultures of a marine-derived fungus Aspergillus glaucus. The structure and stereochemistry of 1 was determined by NMR and X-ray diffraction analyses. Compound 1 showed selective cytotoxicities against A-549, HL-60, BEL-7402, and P388 cell lines.

• 出版日期2007-1-29
• 单位中国海洋大学