A novel aromatic carbocation-based coupling reagent for esterification and amidation reactions

作者:Nguyen Thanh V*; Lyons Demelza J M
来源:Chemical Communications, 2015, 51(15): 3131-3134.
DOI:10.1039/c4cc09539a

摘要

A novel tropylium-based coupling reagent has been developed to facilitate the synthesis of a series of esters, amides, lactones and peptides under mild reaction conditions. Remarkably, this reagent can be used in catalytic amounts in conjunction with a sacrificial reagent, offering a new and efficient method for nucleophilic coupling reactions of carboxylic acids.

  • 出版日期2015

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