alpha/gamma(4)-Hybrid peptide helices: synthesis, crystal conformations and analogy with the alpha-helix

作者:Bandyopadhyay Anupam; Jadhav Sandip V; Gopi Hosahudya N*
来源:Chemical Communications, 2012, 48(57): 7170-7172.
DOI:10.1039/c2cc32911e

摘要

Synthesis, crystal conformations of alpha/gamma(4)-hybrid peptide helices containing proteinogenic amino acid side-chains, and the analogy with the alpha-helix are reported. Results suggest that alpha/gamma(4)-hybrid peptides adopted helical conformations with 12-membered H-bond pseudocycles in single crystals.

  • 出版日期2012