A New 5-Acyl-2-methylpyrrole from the Endophytic Fungus S20 of Cephalotaxus hainanensis

作者：Dai, Wen-jun; Dai, Hao-fu; Wu, Jiao; Liu, Jian; Mei, Wen-li^*

来源：Natural Product Communications, 2009, 4(11): 1489-1490.

• Cephalotaxus hainanensis
• endophytic fungus
• 5-acyl-2-methylpyrrole
• antibacterial activity

A new 5-acyl-2-methylpyrrole, isolated from the endophytic fungus S20 of Cephalotaxus hainanensis, was elucidated as 1-(5-methyl-1H-1-pyrrol-2-yl)-2-((2S*,3R*)-3-((E)-prop-1-enyl)oxiran-2-yl)ethanone (1) on the basis of spectroscopic evidence, including 1D- and 2D-NMR (HMQC, H-1-H-1 COSY, HMBC and ROESY) and MS analysis. Compound I showed inhibitory effects on Staphylococcus aureus and methicillin-resistant S. aureus by the filter paper disc agar diffusion method.

• 出版日期2009-11
• 单位中国热带农业科学院