A clean method for the synthesis of 1,2-disubstituted benzimidazoles through a redox reaction of o-phenylenediamine and aldehydes

作者：Liu, Yunyun^*; Wang, Chunping

来源：Journal of Chemical Research, 2012, (2): 61-62.

DOI：10.3184/174751912X13263910827245

• benzimidazole
• redox
• green synthesis
• iron(III) chloride
• chemo-selective

The reactions of o-phenylenediamine with aromatic aldehydes gave 1,2-disubstituted benzimidazoles in good to excellent yields under mild reaction conditions by using water as the reaction medium in the presence of 20 mol% FeCl3.

• 出版日期2012-2
• 单位江西师范大学