An unexpected twist for autophagy in Crohn's disease

作者:Yano Tamaki*; Kurata Shoichiro
来源:Nature Immunology, 2009, 10(2): 134-136.
DOI:10.1038/ni0209-134

摘要

Autophagy has been linked to inflammatory bowel disease. Studies of two different mouse strains deficient in the autophagy-related gene product Atg16L1 now show that autophagy is important in regulating the secretory function of Paneth cells and the production of inflammatory cytokines in the intestine.

  • 出版日期2009-2

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