Wood dust allergy - prevalence and diagnosis of a rare type-I allergy

作者：Kespohl S^*; Raulf Heimsoth M

来源：Allergologie, 2011, 34(11): 550-554.

DOI：10.5414/ALX01411

• wood dust allergy
• occupational allergens
• in-vitro diagnosis

Wood dust allergy prevalence and diagnosis of a rare type-I allergy Occupational exposure to wood dusts can induce allergic or irritative respiratory problems. In Europe about 3 million workers are exposed to wood dust. The prevalence of wood dust sensitization depends on the processed wood species and varies between 3% for non-tropical wood species and up to 30% for tropical woods. The focus of this paper deals with diagnostic tools to detect IgE-mediated wood dust allergy. Diagnosis of wood dust allergy is often difficult because of a limited number of commercial allergen test solutions and because of cross-reactive carbohydrate determinants (CCDs) influencing in vitro test results. Especially in poly-sensitized patients serological IgE-determination is not sufficient to evaluate the relevance of wood dust sensitization. In addition to work-related or allergen specific challenge tests as "gold standard" and skin prick test are other test systems, like IgE-inhibition-test and basophile activation test (BAT), reasonable tools to identify the causing material of wood dust allergy.

• 出版日期2011-11