A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications

作者：Fu, Xuan; Shang, Wenjing; Wang, Shuaishuai; Liu, Yunpeng; Qu, Jingyao; Chen, Xi; Wang, Peng George^*; Fang, Junqiang^*

来源：Chemical communications, 2017, 53(25): 3555-3558.

DOI：10.1039/c6cc09431g

• PASTEURELLA-MULTOCIDA
• CHEMOENZYMATIC SYNTHESIS
• OROXYLUM-INDICUM
• ACID
• SYNTHASE
• CD44
• SYSTEM
• OLIGOSACCHARIDES
• POLYSACCHARIDE
• POLYMERS

Here, we developed a general strategy for synthesizing homogeneous HA conjugates, and generated homogeneous HA-pNP, HA-biotin, and HA-oroxylin conjugates to investigate the relationships between HA chain length and its diverse biological functions.

• 出版日期2017-3-28
• 单位山东大学