Unique copper-salen complex: an efficient catalyst for N-arylations of anilines and imidazoles at room temperature

作者：Gogoi Ankur; Sarmah Gayatri; Dewan Anindita; Bora Utpal^*

来源：Tetrahedron Letters, 2014, 55(1): 31-35.

DOI：10.1016/j.tetlet.2013.10.084

• Amine
• Arylboronic acid
• Chan-Lam
• Copper
• Imidazole
• Water

We have reported here the catalytic activity of a unique Cu-salen type complex in N-arylation of anilines with arylboronic acids in water. The protocol is found to be applicable for a wide range of electronically diversified arylboronic acids and anilines with excellent yields of the isolated product. Further the scope of this protocol has been extended to the synthesis of various N-aryl imidazoles in iso-propanol.

• 出版日期2014-1-1