Age distribution and metabolic disorders in people with Type 1 diabetes in Beijing and Shantou, China: a cross-sectional study

作者：Huo, L.; Ji, L.^*; Deng, W.; Shaw, J. E.; Zhang, P.; Zhao, F.; McGuire, H. C.; Kissimova-Skarbek, K.; Whiting, D.

来源：Diabetic Medicine, 2018, 35(6): 721-728.

DOI：10.1111/dme.13616

• CARDIOVASCULAR-DISEASE
• PITTSBURGH EPIDEMIOLOGY
• GLYCEMIC CONTROL
• LIFE EXPECTANCY
• HEART-DISEASE
• RISK-FACTORS
• WEIGHT-GAIN
• COMPLICATIONS
• ADOLESCENTS
• PREVALENCE

AimsTo examine whether the age profile of people with Type 1 diabetes differs from that of the general population and in what manner, and to study the clinical characteristics related to metabolic disorders among people with Type 1 diabetes in China.
MethodsWe sequentially enrolled 849 people with Type 1 diabetes from hospital records review, inpatient wards and outpatient clinics. Data were collected via face-to-face interviews, medical records and venous blood samples. Beijing census data for 2011 were used to provide the general population statistics. Descriptive analysis of the results and tests for differences were performed.
ResultsThe median (interquartile range) age at diagnosis of diabetes was 16 (9-28) years and the duration of diabetes was 4 (1-8) years. The mean sd HbA(1c) concentration was 7628 mmol/mol (9.12.5%). Compared with the general population, the population with Type 1 diabetes comprised more young individuals and fewer elderly individuals. The overall prevalence of metabolic syndrome among those with Type 1 diabetes was 10.1% (95% CI 7.9-12.2). People with metabolic syndrome were older and were diagnosed with diabetes at an older age. Hypertension and dyslipidaemia were more common in obese individuals with Type 1 diabetes than in their non-obese counterparts.
ConclusionsCompared with the general population, people with Type 1 diabetes comprised more young and fewer elderly individuals. The prevalence of metabolic syndrome in the Type 1 diabetes population was 10.1%. Hypertension and dyslipidaemia were more prevalent in obese than non-obese individuals.

• 出版日期2018-6
• 单位北京大学; 北京积水潭医院