Acaricidal activities of beta-caryophyllene oxide and structural analogues derived from Psidium cattleianum oil against house dust mites

作者：Oh Min Seok; Yang Ji Yeon; Kim Min Gi; Lee Hoi Seon^*

来源：Pest Management Science, 2014, 70(5): 757-762.

DOI：10.1002/ps.3608

• Dermatophagoides pteronyssinus
• Psidium cattleianum
• beta-caryophyllene oxide
• Dermatophagoides farinae
• house dust mites

BACKGROUND %26lt;br%26gt;This study was to evaluate the acaricidal activities of an active compound isolated from Psidium cattleianum and structural analogues against Dermatophagoides farinae and D. pteronyssinus. beta-Caryophyllene oxide was isolated using chromatographic techniques. %26lt;br%26gt;RESULTS %26lt;br%26gt;Based on the 50% lethal concentration (LD50) values against D. farinae using the fumigant method, beta-caryophyllene oxide (1.36 mu g cm(-2)) was similar to 7.52 times more toxic than benzyl benzoate (10.23 mu g cm(-2)), followed by alpha-caryophyllene (1.75 mu g cm(-2)) and beta-caryophyllene (3.13 mu g cm(-2)). Against D. pteronyssinus, beta-caryophyllene oxide (1.38 mu g cm(-2)) was similar to 7.22 times more toxic than benzyl benzoate (9.96 mu g cm(-2)), followed by alpha-caryophyllene (1.71 mu g cm(-2)) and beta-caryophyllene (3.58 mu g cm(-2)). In the contact toxicity method against D. farinae, beta-caryophyllene oxide (0.44 mu g cm(-2)) was similar to 17.27 times more active than benzyl benzoate (7.60 mu g cm(-2)), followed by alpha-caryophyllene (0.67 mu g cm(-2)) and beta-caryophyllene (0.91 mu g cm(-2)). Against D. pteronyssinus, beta-caryophyllene oxide (0.47 mu g cm(-2)) was similar to 13.06 times more effective than benzyl benzoate (6.14 mu g cm(-2)), followed by alpha-caryophyllene (1.71 mu g cm(-2)) and beta-caryophyllene (3.58 mu g cm(-2)). %26lt;br%26gt;CONCLUSION %26lt;br%26gt;beta-Caryophyllene oxide and structural analogues have potential for development as preventive agents for the control of house dust mites.

• 出版日期2014-5